According to ARRS’ American Journal of Roentgenology (AJR), evaluating chest CT findings presents a further strategy for demonstrating the efficacy of various COVID-19 vaccines in decreasing the impression of a COVID-19 analysis.
Pneumonia frequency and severity had been decrease in sufferers with full vaccination by mRNA and adenovirus vector vaccines experiencing breakthrough infections, as compared with unvaccinated sufferers.”
Davide Bellini, corresponding creator, division of radiological sciences, oncology, and anatomical pathology, “Sapienza” University of Rome
Bellini and colleagues’ single-center examine included 467 sufferers (250 males, 217 ladies; imply age, 65 years) who underwent chest CT between December 15, 2021 and February 18, 2022 throughout hospitalization for symptomatic COVID-19, confirmed by reverse transcriptase-polymerase chain response assay. A complete of 216 sufferers had been unvaccinated, whereas 167 and 84 sufferers had been totally vaccinated-;having obtained a second dose at the very least 14 days earlier than COVID-19 diagnosis-;by the BNT162b2 mRNA vaccine or the ChAdOx1-S adenovirus vector vaccine, respectively.
The frequency of an absence of pneumonia was 15% in unvaccinated sufferers, versus 51% and 29% in sufferers totally vaccinated with BNT162b2 and ChAdOx1-S vaccines, respectively. Additionally, imply CT-SS was considerably greater in unvaccinated sufferers (9.7) than in sufferers totally vaccinated with BNT162b2 (5.2) or ChAdOx1-S (6.2) vaccines (each p<.001).
“The visual observation by radiologic imaging of the protective effect of vaccination on lung injury in patients with breakthrough infections provides additional evidence supporting the clinical benefit of vaccination,” the authors of this AJR article reiterated.
Vicini, S., et al. (2022) Pneumonia frequency and severity in sufferers with symptomatic COVID-19: Impact of mRNA and adenovirus vector vaccines. American Journal of Roentgenology. doi.org/10.2214/AJR.22.27843.
Posted in: Medical Research News | Disease/Infection News
Tags: Adenovirus, Assay, covid-19, CT, Efficacy, Frequency, Imaging, Medical Imaging, Medicine, Oncology, Pathology, Pneumonia, Polymerase, Polymerase Chain Reaction, Radiology, Research, Reverse Transcriptase, Vaccine, X-Ray
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