Open multiplexing with Cell DIVE provides most cancers researchers extra decisions
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New options allow scalability for all researchers with guide or automated workflows

Image credit score: Leica Microsystems GmbH

7 June 2022, Wetzlar, Germany – Leica Microsystems, a number one supplier of microscopy and scientific devices, has launched a brand new technology of its multiplexed imaging answer, Cell DIVE, together with software program and {hardware} enhancements. The extra scalable and environment friendly multiplexing platform addresses spatial cell biology and performance inside the tissue microenvironment, providing researchers the liberty to pick from over 350 rigorously validated antibodies to design their research in their very own means and a confirmed workflow to picture 60+ biomarkers in a single tissue part. 

The new Cell DIVE ClickWell coverslip-free slide holder allows customers to automate their workflows primarily based on their distinctive wants. The improved Cell DIVE workflow reduces the chance of pointless tissue injury and improves pattern processing time whereas nonetheless providing the researcher the liberty to decide on the staining technique that’s greatest for his or her analysis.

“Cell DIVE enables scientists, particularly those working in cancer research, to map normal and diseased tissue by cell type, biomarker profile, and specific features better than ever before,” says James O’Brien, Vice President of Life Sciences at Leica Microsystems. “Cell DIVE with ClickWell powers open multiplexing by making the manual workflow more efficient. It also gives researchers the power to choose their automation strategy to scale their research as it suits them.”

Cell DIVE pattern staining happens off the imager, permitting the consumer to course of many slides by way of staining and dye inactivation steps in batches, thereby enabling scalability even with out automation. ClickWell supplies flexibility for automating pattern staining, enabling using automated pipetting techniques and autostainers. Researchers may also add a robotic arm to assist unattended imaging of many samples.

The Cell DIVE platform was developed for scientists by scientists, enabling life science researchers to construct correct maps of the mobile structure of wholesome and diseased tissues, offering a deeper understanding of the human immune system, utilizing credible information. The know-how has been utilized in over 40 peer-reviewed publications, serving to researchers deepen their understanding of the tissue microenvironment by providing excellent spatial mapping of single cells inside context.

About Leica Microsystems

Leica Microsystems develops and manufactures microscopes and scientific devices for the evaluation of microstructures and nanostructures. Ever for the reason that firm began as a household enterprise within the nineteenth century, its devices have been well known for his or her optical precision and progressive know-how. It is without doubt one of the market leaders in compound and stereo microscopy, digital microscopy, confocal laser scanning microscopy with associated imaging techniques, electron microscopy pattern preparation, and surgical microscopes. 

Leica Microsystems has six main vegetation and product improvement websites around the globe. The firm is represented in over 100 international locations, has gross sales and repair organizations in 20 international locations, and a world community of distribution companions. Its headquarters are situated in Wetzlar, Germany.

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